Engineering of Poly (DL-lactic-co-glycolic acid) Nano-composite Particle for Dry Powder Inhalation Dosage Forms of Insulin with Spray Fluidized Bed Granulating System
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Fibers of Poly (lactic-co-glycolic Acid) / Poly (isoprene) Blend for Application in Tissue Engineering
Tissue engineering can be easily described as the in vitro seeding and attachment of human cells onto a scaffold in order to develop new tissue. The application of polymers as scaffolds may bring interesting properties, such as bioresorbability, biocompatibility, mechanical behavior closer to that presented by the original tissue. Poly (Lactic-coGlycolic Acid) (PLGA) and Poly(Isoprene) (PI) wer...
متن کاملNanosized Mesoporous Bioactive Glass/Poly(lactic-co-glycolic Acid) Composite-Coated CaSiO3 Scaffolds with Multifunctional Properties for Bone Tissue Engineering
It is of great importance to prepare multifunctional scaffolds combining good mechanical strength, bioactivity, and drug delivery ability for bone tissue engineering. In this study, nanosized mesoporous bioglass/poly(lactic-co-glycolic acid) composite-coated calcium silicate scaffolds, named NMBG-PLGA/CS, were successfully prepared. The morphology and structure of the prepared scaffolds were ch...
متن کاملPoly (Lactic-Co-Glycolic) Acid (PLGA) Adjuvant for Immunotherapy
Nowadays, there are several efforts in immunotherapy especially biodegradable and biocompatible nano-polymers are using as immunomodulatory to induce cell mediated immune responses [1]. The advantages of nanoparticles have been proved to be potent immunomodulators in several kinds of vaccines to control a release of antigen, higher quality and quantity of immune responses and protect the integr...
متن کاملAn Overview of Poly(lactic-co-glycolic) Acid (PLGA)-Based Biomaterials for Bone Tissue Engineering
Poly(lactic-co-glycolic) acid (PLGA) has attracted considerable interest as a base material for biomedical applications due to its: (i) biocompatibility; (ii) tailored biodegradation rate (depending on the molecular weight and copolymer ratio); (iii) approval for clinical use in humans by the U.S. Food and Drug Administration (FDA); (iv) potential to modify surface properties to provide better ...
متن کاملLoading of Gentamicin Sulfate into Poly (Lactic-Co-Glycolic Acid) Biodegradable Microspheres
Objective: In dental treatments, use of carriers for targeted antibiotic delivery would be optimal to efficiently decrease microbial count. In this study, gentamicin was loaded into polylactic co-glycolic acid (PLGA) microspheres and its release pattern was evaluated for 20 days. Methods: In this experimental study, PLGA microspheres loaded with gentamycin were produced by the W/O/W method....
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ژورنال
عنوان ژورنال: Journal of the Society of Powder Technology, Japan
سال: 2004
ISSN: 0386-6157,1883-7239
DOI: 10.4164/sptj.41.514